Product Description
Carmellose Calcium
Calcium CMC is calcium salt of Carboxy Methyl Cellulose. It is also popularly known as Carmellose Calcium and Croscarmellose Calcium.
Calcium CMC ( Carmellose Calcium ) is highly pure white powder used for tablet disintegration.
Carboxymethylcellulose Calcium is insoluble in water but it swells in water and Carmellose Calcium used as super disintegrant in pharmaceutical tablet formulation. Calcium CMC helps tablets to disintegrate rapidly and also improves dissolution properties.
Carmellose Calcium performs well with hard tablets where other disintegrants do not perform well
Exceptional Excipient for Pharmaceutical FormulationsCarmellose Calcium is trusted for its superior binding, disintegrating, and matrix-forming capabilities in solid oral dosage forms. It enhances the structural integrity of tablets and ensures consistent drug release and absorption while maintaining compatibility with a wide range of active pharmaceutical ingredients.
Stringent Quality and Safety StandardsManufactured according to BP/USP guidelines, Carmellose Calcium offers a product of high safety and purity. With microbial limits tightly controlled and heavy metals kept below 0.002%, it provides peace of mind for pharmaceutical manufacturers concerned with compliance and patient safety.
Storage and Shelf Life AssuranceThis excipient is non-poisonous and remains stable for up to 36 months when stored in a cool, dry, and well-ventilated environment. Securely packed in 25 kg drums, it maintains its quality throughout its shelf life, ensuring reliable performance in every batch.
FAQ's of Carmellose Calcium:
Q: How is Carmellose Calcium used in pharmaceutical formulations?
A: Carmellose Calcium is commonly utilized as a binder, disintegrant, and matrix former in tablet manufacturing. It facilitates tablet cohesion and controls disintegration, ensuring optimal drug release and absorption profiles.
Q: What are the key quality specifications for Carmellose Calcium?
A: This excipient boasts a purity of over 99.0%, a bulk density of 0.45-0.55 g/cm3, and viscosity of 400-1200 mPas (1% solution). It conforms to BP/USP identification tests, is stable within a pH range of 4-10, and has strict microbial and heavy metal limits.
Q: When should Carmellose Calcium be chosen as a tablet excipient?
A: Carmellose Calcium is ideal when formulating tablets that require rapid dissolution or sustained release. Its versatility as a binder and matrix former makes it suitable for a variety of tablet properties and drug release profiles.
Q: Where is Carmellose Calcium typically stored to preserve its quality?
A: It should be stored in a cool, dry, and well-ventilated place. Proper storage conditions help maintain its chemical integrity and extend its shelf life up to 36 months.
Q: What is the process for confirming the identity and quality of Carmellose Calcium?
A: Each batch undergoes identification testing based on BP/USP monographs, along with rigorous microbiological and heavy metal assessments. These protocols ensure the excipient meets necessary pharmaceutical standards.
Q: What are the benefits of using Carmellose Calcium in tablet production?
A: Its high purity, stable performance across a broad pH range, and excellent binding and disintegrating properties contribute to consistent tablet quality and predictable therapeutic efficacy.