Product Description
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea [6]. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications. For the treatment of osteoarthritis affecting the hip or knee
Chemical Formula: C19H12O8
CAS number; 13739-02-1
Consistent Quality and StabilityDiacerein is produced following GMP guidelines, ensuring a stable and high-quality active pharmaceutical ingredient. With a shelf life of five years under recommended storage conditions, it retains its efficacy and meets strict standards for impurities and heavy metals, making it reliable for pharmaceutical manufacturers and exporters globally.
Precision Identification and Purity AssuranceEach batch of Diacerein is rigorously identified using HPLC and IR methods. The compound must exceed 98% purity and comply fully with pharmacopeial requirements for impurity profiles and residual solvent content. This focus on identification and purity ensures safe and effective use in final drug formulations.
FAQs of Diacerein:
Q: How is Diacerein identified and tested for purity?
A: Diacerein is identified using advanced HPLC (High Performance Liquid Chromatography) and IR (Infrared Spectroscopy) techniques. It is validated to meet not less than 98% purity, and complies with pharmacopeial standards for impurities and ICH guidelines for residual solvents.
Q: What is the packaging type for Diacerein, and how does it maintain stability?
A: Diacerein is supplied in HDPE drums or double LDPE bags. These packaging options safeguard the product against moisture and external contamination, helping maintain stability and potency during storage and transportation.
Q: When and where should Diacerein be stored to ensure maximum shelf life?
A: Diacerein should be stored in a cool and dry place as per recommended conditions. Proper storage helps maintain its stability and extends its shelf life to up to five years from the manufacturing date.
Q: What is the manufacturing process for Diacerein, and why is it important?
A: Diacerein is manufactured according to GMP (Good Manufacturing Practice) guidelines. This process ensures consistency, safety, compliance with quality standards, and suitability as a pharmaceutical ingredient in osteoarthritis treatments.
Q: How is Diacerein used in pharmaceutical formulations?
A: Diacerein acts as a bulk drug/raw material in the production of medicines intended for osteoarthritis. Its proven efficacy and compliance with pharmaceutical regulations make it a preferred choice for manufacturers and traders.
Q: What are the benefits of using Diacerein in osteoarthritis medicine formulations?
A: Using pharmaceutical-grade Diacerein ensures high efficacy, controlled impurity levels, and extended shelf life. These attributes are essential in producing reliable osteoarthritis treatments, enhancing patient safety and therapeutic outcomes.