Indacaterol Maleate

Product Description

Indacaterol maleate is used for the treatment of Chronic Obstructive Pulmonary Disease (COPD). It is delivered as an aerosol formulation through a dry powder inhaler. It has a role as a beta-adrenergic agonist and a bronchodilator agent. The maleate salt is obtained by reaction of Indacaterol with one equivalent of Maleic acid. Indacaterol inhalation comes as a powder-filled capsule to inhale by mouth using a special inhaler.Indacaterol works by stimulating adrenergic beta-2 receptors in the smooth muscle of the airways. This causes relaxation of the muscle, thereby increasing the diameter of the airways, which become constricted in asthma and COPD. It is also long-acting due to its high affinity to the lipid raft domains in the airway membrane so it slowly dissociates from the receptors. Indacaterol also has a high intrinsic efficacy, so it is also very rapid acting.