CAS number: 88495-63-0
Chemical Formula: C19H28O8
For the treatment of severe malaria caused by Plasmodium falciparum in adults and children Artesunate is an artemisinin drug capable of killing all erythrocytic stages of the malaria parasite including the ring stage, late schizonts, and the gametocytes responsible for transmission of malaria . It also increases splenic clearance of infected erythrocytes by reducing cytoadherence. Artesunate and the artemisinins are the most rapid acting anti-malarial drugs. This class of drugs is ineffective against extra-erythrocytic forms, sporozoites, liver schizonts, and merozoites.