Product Description
Croscarmellose Sodium
DESCRIPTION
Crosslinked Polymer of Carboxy Methyl Cellulose Sodium
White Fibrous Powder
Odorless
Insoluble and Highly absorbent product with good Swelling Properties
APPLICATIONS
Used as Disintegrant in Capsules, Tablet and Granule Formulations.
STORAGE
Stored in Well Closed Container at Cool and Dry Place as Croscarmellose Sodium is Hygroscopic by Nature.
Packaging & Shipping
Effective Tablet DisintegrationCroscarmellose Sodium is essential for ensuring rapid tablet break-up in the digestive tract, providing faster therapeutic effects in pharmaceutical formulations. Its high water absorption capacity allows tablets to disintegrate swiftly, making it ideal for oral solid dosage forms. The consistent particle size and purity guarantee optimal performance in tablet manufacturing processes.
Stringent Quality and Safety StandardsThis excipient adheres to global pharmacopoeia standards (USP/NF, Ph.Eur, JP), with strict controls on microbial limits, endotoxin levels, and residual solvents. It is non-poisonous, free from foreign particles, and contains very low levels of starch, chloride, heavy metals, and moisture, ensuring it is safe for use in pharmaceutical products worldwide.
FAQs of Croscarmellose Sodium:
Q: How is Croscarmellose Sodium used in tablet formulations?
A: Croscarmellose Sodium is primarily used as a disintegrant in tablet formulations. It promotes rapid tablet disintegration by absorbing water and swelling, which enables quick release of the active pharmaceutical ingredient for effective therapeutic action.
Q: What are the benefits of using Croscarmellose Sodium in pharmaceuticals?
A: Its high water absorption and swelling capability ensure efficient and fast tablet disintegration. This enhances patient compliance and improves drug bioavailability by facilitating prompt dissolution of the medication in the digestive tract.
Q: Where should Croscarmellose Sodium be stored to maintain its quality?
A: It should be stored in a cool, dry place, with the packaging tightly closed, to preserve its properties and prevent moisture absorption. Proper storage extends the shelf life up to 23 years.
Q: What quality standards does Croscarmellose Sodium comply with?
A: Croscarmellose Sodium is manufactured in compliance with USP/NF, Ph.Eur, and JP standards. It also meets strict limits for microbial contamination, endotoxins, residual solvents, and heavy metals, ensuring pharmaceutical-grade safety and purity.
Q: How is Croscarmellose Sodium supplied and packed?
A: The product is typically distributed, exported, or supplied in 25 kg HDPE drums or bags. These packaging options safeguard the powder from moisture and contaminants during transportation and storage.
Q: Is Croscarmellose Sodium safe for pharmaceutical use?
A: Yes, it is considered non-poisonous and safe for use in pharmaceutical formulations. It contains minimal heavy metals, is free from foreign particles, and its microbial counts are well within safe limits, making it suitable for oral medications.