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Silodosin

Silodosin

Product Details:

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Price And Quantity

  • INR
  • 1 kg Kilograms

Trade Information

  • mumbai
  • Cheque, Telegraphic Transfer (T/T), Paypal
  • 100 Kilograms kg Per Week
  • 1 Week
  • All India

Product Description

CAS number: 160970-54-7

Chemical Formula: C25H32F3N3O4

Treatment for symptomatic relief of benign prostatic hyperplasiaBenign prostate hyperplasia (BPH), or an enlarged prostate, is a condition found only in men and is characterized by a non-cancerous enlargement of the prostate gland. Symptoms of BPH include urinary difficulty, urinary frequency and an inability to complete bladder emptying. Silodosin is highly uroselective for the alpha (1A) receptors located in the prostate, [urethrea and bladder trigone in the lower urinary tract]. Blocking these receptors relaxes the smooth muscles, resulting in an improvement in urine flow and a reduction in BPH symptoms. The selective binding of silodosin to the alpha (1A) receptors is substantially greater than the binding to the cardiovascular-associated alpha (1B) receptors and thereby maximizes target organ activity while minimizing the potential for blood pressure effects. [Watson Pharmaceutical Inc. Press release] Silodosin is alpha 1A-adrenoceptor selective antagonist which inhibits sympathetic nerve stimulation and relaxation of smooth muscle tone in the lower urinary tract which relieves the pressure from contraction of smooth muscle. The reduction of intraurethral pressure improves voiding and storage issues associated with BPH.



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