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Mebendazole pharmaceutical raw material
Product Details:
- Boiling point Not applicable / decomposes
- Solubility Practically insoluble in water, soluble in chloroform and slightly soluble in ethanol
- Particle Size 95% Passes through 80 mesh
- EINECS No 250-635-4
- Poisonous No (when used as directed in pharmaceuticals)
- Molecular Weight 295.3 g/mol
- HS Code 29332990
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Mebendazole pharmaceutical raw material Price And Quantity
- INR
- 1 kg Kilograms
Mebendazole pharmaceutical raw material Product Specifications
- Store in a cool, dry place away from direct sunlight and moisture
- Pharma Grade
- NMT 0.5%
- 288-292C
- White to Off-white
- Pharmaceutical Raw Material
- Tasteless
- Neutral (approx. pH 7)
- Odorless
- Methyl 5-benzoyl-2-benzimidazolecarbamate
- NMT 0.001%
- C16H13N3O3
- 5 Years if properly stored
- (Displayed as per chemical structure see product image for visual representation)
- White to Off-white Powder
- 250-635-4
- Powder
- No (when used as directed in pharmaceuticals)
- 295.3 g/mol
- 29332990
- Mebendazole
- 99% Min
- Practically insoluble in water, soluble in chloroform and slightly soluble in ethanol
- Not applicable / decomposes
- 31431-39-7
- Used as an antihelminthic agent in the treatment of nematode and roundworm infestations
- 95% Passes through 80 mesh
Mebendazole pharmaceutical raw material Trade Information
- mumbai
- Contact us for information regarding our sample policy
- All India
Product Description
Mebendazole ip/bp/usp
CAS number : 31431-39-7
Chemical Formula : C16H13N3O3
For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections. Mebendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.
Chemical Formula : C16H13N3O3
For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections. Mebendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.
Exceptional Purity and Compliance
Mebendazole pharmaceutical raw material adheres to rigorous pharmacopeial regulations, ensuring consistent quality, high assay (minimum 99% purity), and compliance with microbial and heavy metal limits. Each batch is meticulously tested to guarantee optimal performance in pharmaceutical applications.
Robust Stability and Longevity
Packaged in 25kg Fiber or HDPE drums, Mebendazole remains stable for up to five years when stored properly. Its physical and chemical stability is maintained in cool, dry environments, providing reliability for manufacturers and distributors worldwide.
Versatile Antihelminthic Usage
Mebendazoles primary use is as an effective antihelminthic, targeting various nematode and roundworm infestations. Its tasteless, odorless powder form enables easy formulation and integration into pharmaceutical preparations, delivering therapeutic benefits in a range of medicinal products.
FAQs of Mebendazole pharmaceutical raw material:
Q: How is Mebendazole pharmaceutical raw material commonly used?
A: Mebendazole is primarily used as an antihelminthic agent for treating infestations by nematodes and roundworms. It is formulated into pharmaceutical products such as tablets or suspensions for oral administration.Q: What forms of packaging are available for Mebendazole raw material?
A: Mebendazole is supplied in robust 25kg Fiber Drums or HDPE Drums, ensuring product safety and stability during storage and transportation.Q: What are the storage recommendations for Mebendazole?
A: To maintain its stability and efficacy, Mebendazole should be stored in a cool, dry place away from direct sunlight and moisture. Following these guidelines helps the material retain its quality for up to five years.Q: How can I verify the purity and quality of supplied Mebendazole?
A: Purity and quality are confirmed by strict adherence to pharmacopeial standards, including assay (98.5%101.0% on dried basis), minimal related substances (NMT 0.5%), and compliance with microbial and heavy metal limits. Certificates of analysis accompany each batch.Q: What is the benefit of using pharma-grade Mebendazole?
A: Using pharma-grade Mebendazole guarantees high purity, reliable performance in medicinal formulations, and adherence to global regulatory standards, maximizing both therapeutic efficacy and patient safety.Q: When is the products shelf life valid until?
A: Mebendazole offers a five-year shelf life from the date of manufacture, provided it is stored correctly in its original packaging.Q: Where can Mebendazole be sourced from?
A: This raw material is available from reputable manufacturers, distributors, exporters, suppliers, and traders based in India, catering to global pharmaceutical markets.Tell us about your requirement
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