Pepsin splits proteins into water-soluble fragments called peptones. Although this ordinarily occurs in the stomach, it can be duplicated in a large reaction vessel on a commercial purpose. Partial digestion by pepsin can be used in food applications, for instance, in the processing of proteins and gelatin. Pepsin has been used as a substitute for rennin in the production of the cheese.
Pepsin is used by theÂ leather industryÂ to remove undesirable traces of remaining tissue, such as hair and fat, from partially processed hides. This enzymatic treatment is called bating the hides. The process also dwells and softens the hides, improving leather quality.